If a piece of plaque breaks off, a blood clot can form around it, obstructing blood flow and oxygen supply to the heart. This can damage the heart muscle and be life-threatening. You've probably heard of the term “hardening of the arteries,” which is the same as calcification.
Coronary artery calcification
causes arteries to harden and are less able to expand and contract.This increases the risk of cardiovascular problems. Coronary artery calcifications occur when calcium builds up in the arteries that supply blood to the heart. This buildup can cause coronary artery disease and increase the risk of having a heart attack.
Coronary calcification
occurs when calcium builds up in plaque found in the walls of the coronary arteries, which supply blood to the heart muscle.The presence of coronary calcification may be an early sign of coronary artery disease, which can cause a heart attack. .
Coronary artery calcification
is an indicator of coronary artery disease and can provide information to your healthcare provider to help you assess your cardiovascular risk. Coronary calcification isn't reversible, but you can prevent it from getting worse by making lifestyle changes, such as not smoking, controlling blood pressure and cholesterol, and maintaining a healthy weight.Recent advances have identified microRNAs (MIRs) as key regulators of CAC by directing the complex genetic reprogramming of smooth muscle cells (MSM) and the functional responses of other related cell types relevant to vascular calcification. Men experience coronary artery calcifications at an earlier age than women, about 10 to 15 years earlier. In terms of the pathophysiology of CAC, the factors governing the formation of intimate versus medial calcification are not fully understood, and the clinical importance of these two types of CAC has not yet been clarified. Read on to discover why and how coronary artery calcification occurs, as well as tips for prevention and treatment.
If calcifications show no signs of serious illness, the doctor will usually recommend modifying the risk factors. In fact, the VSMC plays an integral role in this process by transdifferentiating into osteoblast-like cells, producing calcifying matrix vesicles, and secreting factors that decrease the activity of osteoclast-like cells capable of resorbing minerals. Unfortunately, they may only be able to see calcification when there is a significant buildup of calcium in the coronary arteries. Knowing if you have coronary artery calcification can help your healthcare provider make a plan for how to help you.
Heart-healthy habits, such as a low-fat diet and exercise, can help reduce the risk of calcifications and other chronic health conditions. Maintaining a healthy lifestyle and controlling chronic diseases can help reduce the risk of coronary artery calcifications. The TAXUS-IV trial (slow-release, polymer-based, paclitaxel-releasing stent) was a prospective, double-blind, randomized, multicenter study that examined the impact of calcified lesion on clinical and angiographic outcomes after the implantation of the paclitaxel-releasing stent. Researchers believe that coronary artery calcifications may occur due to the release of calcium when smooth muscle cells die in the heart's arteries.
On the other hand, renal dysfunction (mainly the reduction of glomerular filtration rate), hypercalcemia, hyperphosphatemia, parathyroid hormone abnormalities and the duration of dialysis are related to medial calcification. .
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